Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28076884 | 0.87 | SLC6A4 (0.52) | HTR1ASLC6A4OPRM1CCR3RYR2 | |
| SCHEMBL28076582 | 0.84 | CYP2D6 (0.55) | HTR1ASLC6A4RYR2 | |
| SCHEMBL28076537 | 0.82 | HTR4 (0.45) | HTR1ASLC6A4OPRM1CCR3HTR2A | |
| SCHEMBL27997715 | 0.82 | HTR4 (0.47) | HTR1ASLC6A4OPRM1CCR3HTR2A | |
| SCHEMBL28830757 | 0.81 | TSHR (0.60) | — | |
| SCHEMBL28076795 | 0.80 | HTR1A (0.46) | HTR1ASLC6A4CCR3RYR2 | |
| SCHEMBL28076801 | 0.79 | HTR1A (0.52) | HTR1ASLC6A4CCR3RYR2 | |
| SCHEMBL28076704 | 0.78 | GAA (0.56) | HTR1ASLC6A4CCR3 | |
| SCHEMBL28076771 | 0.77 | HTR1A (0.52) | HTR1ASLC6A4RYR2 | |
| SCHEMBL28076596 | 0.75 | HTR1A (0.54) | HTR1ASLC6A4CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980184-B | Piperidine compounds, medical composition and its use containing this compound | 爱思开生物制药株式会社 | 2016-08-24 | — | — | CN | disclosed |