Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571987 | 0.74 | NOS2 (0.48) | NOS2MAPKAPK2 | |
| SCHEMBL3195239 | 0.72 | HRH1 (0.39) | NOS2MAPKAPK2 | |
| SCHEMBL10924823 | 0.71 | TLR8 (0.44) | NOS2 | |
| SCHEMBL28173007 | 0.71 | KDM1A (0.38) | — | |
| SCHEMBL6753235 | 0.69 | TLR7 (0.46) | NOS2 | |
| SCHEMBL28076490 | 0.69 | TLR7 (0.41) | NOS2MAPKAPK2 | |
| SCHEMBL13412472 | 0.69 | NUDT1 (0.49) | NOS2MAPKAPK2 | |
| SCHEMBL30154935 | 0.69 | — | — | |
| SCHEMBL8055376 | 0.69 | — | — | |
| SCHEMBL15740547 | 0.68 | DHFR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658646-A | Aminoheteroaryl benzamides as kinase inhibitors | 诺华股份有限公司 | 2016-06-08 | — | — | CN | disclosed |