Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.39 |
| ▸ | HRH2 | P25021 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 5/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 4/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717192 | 0.84 | HRH1 (0.45) | HRH1HRH4HRH2HRH3 | |
| SCHEMBL4333718 | 0.79 | — | — | |
| SCHEMBL28571987 | 0.78 | NOS2 (0.48) | MAPKAPK2NOS2USP2LMNANOS3 | |
| SCHEMBL10924823 | 0.75 | TLR8 (0.44) | HRH3NOS2NOS3 | |
| SCHEMBL20240844 | 0.73 | HRH1 (0.38) | HRH1HRH4HRH2HRH3TDP1 | |
| SCHEMBL4366845 | 0.73 | HRH1 (0.47) | HRH1HRH4HRH2HRH3TDP1 | |
| SCHEMBL13412472 | 0.73 | NUDT1 (0.49) | MAPKAPK2NOS2NOS3NUDT1NOS1 | |
| SCHEMBL6753235 | 0.73 | TLR7 (0.46) | TDP1NOS2USP2 | |
| SCHEMBL28076490 | 0.73 | TLR7 (0.41) | TDP1MAPKAPK2NOS2LMNANOS3 | |
| SCHEMBL3938944 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080299038-A1 | Luminescent Metal Complexes for Monitoring Renal Function | MALLINCKRODT INC. (US) | 2008-12-04 | — | — | US | claimed |
| CN-101010107-A | Luminescent metal complexes for monitoring renal function | MALLINCKRODT INC (US) | 2007-08-01 | — | — | CN | claimed |
| EP-1793866-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | MALLINCKRODT, INC. (US) | 2007-06-13 | — | — | EP | claimed |
| WO-2006026038-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | MALLINCKRODT INC. (US) | 2006-03-09 | — | — | WO | claimed |
| US-20100113756-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | MALLINCKRODT INC. (US) | 2010-05-06 | — | — | US | disclosed |
| US-7674902-B2 | Luminescent metal complexes for monitoring renal function | MALLINCKRODT INC. (US) | 2010-03-09 | — | — | US | disclosed |
| US-20080299038-A1 | Luminescent Metal Complexes for Monitoring Renal Function | MALLINCKRODT INC. (US) | 2008-12-04 | — | — | US | disclosed |
| CN-101010107-A | Luminescent metal complexes for monitoring renal function | MALLINCKRODT INC (US) | 2007-08-01 | — | — | CN | disclosed |
| EP-1793866-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | MALLINCKRODT, INC. (US) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006026038-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | MALLINCKRODT INC. (US) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080299038-A1 | Luminescent Metal Complexes for Monitoring Renal Function | REN, GLS, ATP6V1B1 | HRH1 2021/4885HRH4 1227/4885HRH2 1837/4885 |
| US-20100113756-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | REN, GLS, ATP6V1B1 | HRH1 1906/4885HRH4 1074/4885HRH2 1644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.