Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | DRD4 | P21917 | 5/20 | 0.59 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28830809 | 0.90 | DRD4 (0.62) | DRD4CACNA1GGAAMEN1KMT2A | |
| SCHEMBL28076585 | 0.85 | DRD4 (0.58) | DRD4GAAMEN1KMT2AUSP2 | |
| SCHEMBL28076710 | 0.84 | TSHR (0.52) | TSHRDRD4CACNA1GGAAMEN1 | |
| SCHEMBL27997731 | 0.84 | TSHR (0.52) | TSHRDRD4CACNA1GGAAMEN1 | |
| SCHEMBL28076582 | 0.82 | CYP2D6 (0.55) | DRD4GAACYP2D6 | |
| SCHEMBL28076798 | 0.81 | HTR1A (0.55) | — | |
| SCHEMBL28076624 | 0.80 | HTR1A (0.52) | DRD4GAAMEN1KMT2APOLB | |
| SCHEMBL28076884 | 0.80 | SLC6A4 (0.52) | TSHR | |
| SCHEMBL28076704 | 0.79 | GAA (0.56) | DRD4GAAMEN1KMT2ACYP2D6 | |
| SCHEMBL28076620 | 0.78 | HTR1A (0.46) | TSHRDRD4GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980184-B | Piperidine compounds, medical composition and its use containing this compound | 爱思开生物制药株式会社 | 2016-08-24 | — | — | CN | disclosed |