Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28076657 | 0.76 | HTR2A (0.38) | CD274FFAR4HRH3HTR2ADHFR | |
| SCHEMBL28076877 | 0.72 | HRH3 (0.42) | CD274HRH3HTR2ATAAR1 | |
| SCHEMBL28076654 | 0.70 | CD274 (0.40) | CD274AKT2FFAR4HRH3NPC1 | |
| SCHEMBL657575 | 0.70 | ALDH1A1 (0.46) | SMN1; SMN2POLBLMNAHTR1AALDH1A1 | |
| SCHEMBL112586 | 0.68 | LMNA (0.44) | NPC1POLBLMNAALDH1A1KDM4E | |
| SCHEMBL22866559 | 0.66 | CD274 (0.61) | CD274AKT2HRH3TAAR1PDCD1 | |
| SCHEMBL25570163 | 0.66 | HTR2A (0.42) | FFAR4HTR2ADHFR | |
| SCHEMBL13156334 | 0.65 | HIF1A (0.44) | HTR2AALDH1A1KDM4E | |
| SCHEMBL8123158 | 0.64 | DHFR (0.37) | SMN1; SMN2POLBLMNAHTR2AALDH1A1 | |
| SCHEMBL435089 | 0.63 | LMNA (0.49) | NPC1SMN1; SMN2POLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103965147-B | Benzofuran derivatives | 武田药品工业株式会社 | 2016-08-24 | — | — | CN | disclosed |