Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.32 |
| ▸ | ARNT | P27540 | 3/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17815796 | 0.74 | PRMT1 (0.53) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL28476642 | 0.73 | BCL6 (0.41) | MAPTHTTALDH1A1CA1CA2 | |
| SCHEMBL29129582 | 0.73 | MAPT (0.52) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL2708359 | 0.72 | ALDH1A1 (0.38) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL563457 | 0.71 | ALDH1A1 (0.40) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL563456 | 0.71 | ALDH1A1 (0.40) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL12138409 | 0.69 | ALDH1A1 (0.44) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL304703 | 0.68 | HCAR3 (0.39) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL304702 | 0.68 | HCAR3 (0.39) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL1742858 | 0.68 | MAPT (0.39) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105753863-A | Oxo-dihydroimidazopyridine compound and application thereof | 东莞市真兴贝特医药技术有限公司 | 2016-07-13 | — | — | CN | disclosed |