Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4862437 | 0.87 | ALDH1A1 (0.39) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Acetic Acid SCHEMBL10338274 | 0.86 | FFAR3 (0.37) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Acetic Acid SCHEMBL813643 | 0.86 | FFAR3 (0.37) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Glycolic Acid SCHEMBL28435875 | 0.86 | ALDH1A1 (0.37) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Acetic Acid SCHEMBL2578978 | 0.86 | FFAR3 (0.37) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Acetic Acid SCHEMBL11542884 | 0.86 | FFAR3 (0.37) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Carbamic Acid SCHEMBL28113270 | 0.86 | ACHE (0.37) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL3096124 | 0.85 | ALDH1A1 (0.39) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL15930 | 0.85 | ALDH1A1 (0.39) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Succinic Acid SCHEMBL28992615 | 0.84 | LMNA (0.45) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106631779-B | Polyol esters and their use in processing halogenated vinyl polymers | 济南金昌树新材料科技有限公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-103153952-B | The oxime ester derivative of benzo carbazole compound and in photopolymerisable compositions as the purposes of photoinitiator | 巴斯夫欧洲公司 | 2016-07-13 | — | — | CN | disclosed |