Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.50 |
| ▸ | CA2 | P00918 | 13/20 | 0.50 |
| ▸ | CA9 | Q16790 | 13/20 | 0.50 |
| ▸ | CA12 | O43570 | 8/20 | 0.50 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.49 |
| ▸ | CA6 | P23280 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | DKK1 | O94907 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550093 | 0.85 | LMNA (0.58) | CA1CA2CA9CA12CA14 | |
| SCHEMBL28746782 | 0.79 | LMNA (0.70) | CA1CA2CA9CA12SOS1 | |
| SCHEMBL566973 | 0.78 | LMNA (0.58) | CA1CA2CA9CA12MEN1 | |
| SCHEMBL31203257 | 0.78 | LMNA (0.58) | CA1CA2CA9CA12MEN1 | |
| SCHEMBL12278421 | 0.78 | SOS1 (0.58) | CA1CA2CA9CA12SOS1 | |
| Hydrochloric Acid SCHEMBL22129912 | 0.77 | LMNA (0.56) | CA1CA2CA9CA12MEN1 | |
| SCHEMBL18311786 | 0.77 | ALDH1A1 (0.63) | MEN1KMT2AROCK1 | |
| SCHEMBL24125025 | 0.75 | IMPDH2 (0.45) | — | |
| SCHEMBL27823663 | 0.74 | CA2 (0.58) | CA1CA2CA9CA12SOS1 | |
| SCHEMBL28107398 | 0.74 | SOS1 (0.70) | CA1CA2CA9CA12SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764510-A | An H3 receptor antagonist combined with a cholinesterase inhibitor for use in the treatment of alzheimer's disease | 赛诺菲 | 2016-07-13 | — | — | CN | disclosed |