SCHEMBL28077706

SCHEMBL28077706

O=C(O)C(C(=O)c1ccccc1)C1CCCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.50
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
LMNA P02545 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 1/20 0.41
HTR1E P28566 1/20 0.41
S1PR3 Q99500 1/20 0.41
TSHR P16473 2/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
SCN1A P35498 1/20 0.40
SCN2A Q99250 1/20 0.40
SCN3A Q9NY46 1/20 0.40
MME P08473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28833134 0.96 MCL1 (0.46) MCL1NPC1RAB9ATDP1L3MBTL1
SCHEMBL28077720 0.82 TSHR (0.57) LMNAMEN1KMT2ATSHRCYP1A2
SCHEMBL29770503 0.79 NPC1 (0.46) MCL1NPC1RAB9ATDP1L3MBTL1
SCHEMBL28077872 0.79 TSHR (0.64) NPC1L3MBTL1LMNAMEN1KMT2A
SCHEMBL8391560 0.78 NPC1 (0.42) MCL1NPC1RAB9ATDP1L3MBTL1
SCHEMBL522599 0.78 LMNA (0.46) MCL1NPC1RAB9ATDP1L3MBTL1
SCHEMBL29291723 0.78 DPP8 (0.51) MCL1NPC1RAB9ATDP1L3MBTL1
Benzene SCHEMBL7894864 0.78 EPHX1 (0.44) RAB9AL3MBTL1LMNAMEN1KMT2A
SCHEMBL27759418 0.77 SLC6A3 (0.50) MCL1L3MBTL1LMNAMEN1KMT2A
SCHEMBL2477876 0.76 LMNA (0.49) NPC1RAB9ALMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105753682-A Preparation method of cyclopentyl phenyl ketone 中国科学院成都有机化学有限公司 2016-07-13 CN disclosed