⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16670028 | 0.80 | HCAR2 (0.31) | — | |
| SCHEMBL11395453 | 0.70 | CCR1 (0.31) | — | |
| SCHEMBL286168 | 0.63 | RAPGEF4 (0.31) | — | |
| SCHEMBL19573877 | 0.62 | — | — | |
| SCHEMBL11067034 | 0.60 | — | — | |
| SCHEMBL16677174 | 0.60 | — | — | |
| SCHEMBL191997 | 0.60 | — | — | |
| SCHEMBL18185780 | 0.57 | LMNA (0.32) | — | |
| SCHEMBL9332355 | 0.57 | — | — | |
| SCHEMBL16669983 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105859643-B | A kind of 2- ethyl -3,5, the synthetic method of 6- trimethylpyrazine | 平光制药股份有限公司 | 2018-11-16 | — | — | CN | claimed |
| CN-105859643-A | Synthetic method of 2-ethyl-3,5,6-trimethyl pyrazine | 平光制药股份有限公司 | 2016-08-17 | — | — | CN | claimed |
| EP-4613744-A1 | HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Guangdong Zhongke Medicine Research Ltd. (CN) | 2025-09-10 | — | — | EP | disclosed |
| CN-115991698-B | Heterocyclic compound and preparation method and application thereof | 广东中科药物研究有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117586227-A | Pirfenidone derivative and preparation method and application thereof | 广东中科药物研究有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-115991698-A | Heterocyclic compound and preparation method and application thereof | 广东中科药物研究有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-108558833-B | Pyrazole alcohol compound, pharmaceutical composition thereof and application thereof in medicines | 贵州医科大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-105859643-B | A kind of 2- ethyl -3,5, the synthetic method of 6- trimethylpyrazine | 平光制药股份有限公司 | 2018-11-16 | — | — | CN | disclosed |
| CN-105859643-B | A kind of 2- ethyl -3,5, the synthetic method of 6- trimethylpyrazine | 平光制药股份有限公司 | 2018-11-16 | — | — | CN | disclosed |
| CN-105859643-A | Synthetic method of 2-ethyl-3,5,6-trimethyl pyrazine | 平光制药股份有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-105859643-A | Synthetic method of 2-ethyl-3,5,6-trimethyl pyrazine | 平光制药股份有限公司 | 2016-08-17 | — | — | CN | disclosed |