Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4517767 | 0.82 | BCAT2 (0.51) | ABL1 | |
| SCHEMBL28078756 | 0.81 | IKBKB (0.54) | IKBKBCA1CA2PTGES2 | |
| SCHEMBL28078718 | 0.81 | IKBKB (0.65) | IKBKBCA1CA2 | |
| SCHEMBL2311228 | 0.77 | ABL1 (0.53) | ABL1CA1CA2BCRPTGES2 | |
| SCHEMBL17784452 | 0.76 | IKBKB (0.67) | IKBKBCA1CA2 | |
| SCHEMBL8075337 | 0.76 | CA2 (0.55) | ABL1CA1CA2BCRPTGES2 | |
| SCHEMBL5498010 | 0.76 | BCAT2 (0.54) | — | |
| Hydrochloric Acid SCHEMBL5797907 | 0.75 | FFAR4 (0.46) | IKBKBABL1 | |
| SCHEMBL28312072 | 0.74 | IKBKB (0.54) | IKBKBCA1CA2PTGES2 | |
| SCHEMBL28312069 | 0.74 | IKBKB (0.54) | IKBKBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683157-B | Sulfonamides as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-105683157-A | Sulfonamides as modulators of sodium channels | 沃泰克斯药物股份有限公司 | 2016-06-15 | — | — | CN | disclosed |