Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 8/20 | 0.65 |
| ▸ | CHUK | O15111 | 6/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28078565 | 0.88 | IKBKB (0.65) | IKBKBCHUKCA2CA12CA9 | |
| SCHEMBL17784452 | 0.86 | IKBKB (0.67) | IKBKBCHUKCA2CA12CA9 | |
| SCHEMBL28078756 | 0.84 | IKBKB (0.54) | IKBKBCA2CA12CA9CA1 | |
| SCHEMBL28312072 | 0.84 | IKBKB (0.54) | IKBKBCHUKCA2CA12CA9 | |
| SCHEMBL28078710 | 0.81 | IKBKB (0.51) | IKBKBCA2CA1 | |
| SCHEMBL14566317 | 0.79 | IKBKB (1.00) | IKBKBCHUKMAPK12LRRK2IKBKE | |
| SCHEMBL28078713 | 0.78 | CA2 (0.54) | IKBKBCA2CA12CA9CA1 | |
| SCHEMBL7113271 | 0.77 | IKBKB (0.56) | IKBKBCHUKCA2CA12CA9 | |
| SCHEMBL28032548 | 0.76 | CA2 (0.73) | CA2CA12CA9CA1LRRK2 | |
| SCHEMBL28312071 | 0.75 | IKBKB (0.54) | IKBKBCHUKCA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683157-A | Sulfonamides as modulators of sodium channels | 沃泰克斯药物股份有限公司 | 2016-06-15 | — | — | CN | disclosed |