Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.53 |
| ▸ | BCR | P11274 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311184 | 0.80 | LRRK2 (0.56) | PTGS2PTGS1CA2CA1CA12 | |
| SCHEMBL2304522 | 0.77 | KIF11 (0.46) | CA2CA1PTGES2CA12CA9 | |
| SCHEMBL18118195 | 0.77 | PTGS2 (0.68) | ABL1BCRPTGS2PTGS1CA2 | |
| SCHEMBL28078710 | 0.77 | IKBKB (0.51) | ABL1BCRCA2CA1PTGES2 | |
| SCHEMBL6622402 | 0.76 | PTGS2 (0.44) | ABL1BCRPTGS2PTGS1CA2 | |
| SCHEMBL8075337 | 0.76 | CA2 (0.55) | ABL1BCRCA2CA1PTGES2 | |
| SCHEMBL30434205 | 0.75 | CA2 (0.64) | PTGS2PTGS1CA2CA1CA12 | |
| SCHEMBL1137645 | 0.75 | PTGS2 (0.65) | ABL1BCRPTGS2PTGS1CA2 | |
| SCHEMBL2311233 | 0.75 | CA2 (0.62) | ABL1BCRCA2CA1 | |
| SCHEMBL1069088 | 0.74 | CA12 (0.49) | PTGS2PTGS1CA2CA1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349990-A1 | ARYL-PHENYL-SULFONAMIDE-PHENYLENE COMPOUNDS AND THEIR USE | Pimco 2664 Limited (GB) | 2011-08-03 | — | — | EP | disclosed |