Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.56 |
| ▸ | CHUK | O15111 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 10/20 | 0.42 |
| ▸ | CA1 | P00915 | 9/20 | 0.42 |
| ▸ | CA9 | Q16790 | 7/20 | 0.41 |
| ▸ | CA12 | O43570 | 6/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720385 | 0.83 | CA2 (0.47) | IKBKBCHUKCA2CA1CA9 | |
| SCHEMBL17784452 | 0.81 | IKBKB (0.67) | IKBKBCHUKCA2CA1CA9 | |
| SCHEMBL16719394 | 0.80 | IKBKB (0.44) | IKBKB | |
| SCHEMBL28078565 | 0.80 | IKBKB (0.65) | IKBKBCHUKCA2CA1CA9 | |
| SCHEMBL3165969 | 0.80 | BAZ2B (0.44) | BRD4 | |
| SCHEMBL4638595 | 0.79 | HPGDS (0.46) | — | |
| SCHEMBL4631064 | 0.79 | TLR8 (0.45) | BRD4MAPT | |
| SCHEMBL2637648 | 0.78 | BCAT2 (0.61) | IKBKBCHUKBRD4MAPT | |
| SCHEMBL28078718 | 0.77 | IKBKB (0.65) | IKBKBCHUKCA2CA1CA9 | |
| SCHEMBL4916850 | 0.77 | PARP1 (0.49) | IKBKBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | claimed |
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | APOB, F12, SERPINB1 | IKBKB 28/4885CHUK 61/4885CA2 3516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.