Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.45 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3024115 | 0.81 | PARP10 (0.67) | PARP10PARP15PARP14ALDH1A1KMT2A | |
| SCHEMBL3643463 | 0.78 | PARP10 (0.67) | PARP10PARP15PARP14ALDH1A1KMT2A | |
| SCHEMBL6388320 | 0.76 | PKM (0.77) | CA12CA1CA2CA9PARP10 | |
| SCHEMBL11446022 | 0.75 | PKM (0.66) | CA2PARP10PKMSOS1ALDH1A1 | |
| SCHEMBL3016749 | 0.75 | PARP10 (0.79) | CA1CA2PARP10SOS1PARP15 | |
| SCHEMBL8743797 | 0.75 | SLC9A1 (0.54) | — | |
| SCHEMBL2778224 | 0.74 | ACLY (0.51) | CA12CA1CA2CA9PKM | |
| Hydrochloric Acid SCHEMBL8743803 | 0.74 | SLC9A1 (0.53) | — | |
| SCHEMBL3314857 | 0.73 | PARP10 (0.63) | CA1CA2PARP10SOS1PARP15 | |
| SCHEMBL8641351 | 0.73 | EPAS1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683157-A | Sulfonamides as modulators of sodium channels | 沃泰克斯药物股份有限公司 | 2016-06-15 | — | — | CN | disclosed |