SCHEMBL28079301

SCHEMBL28079301

Nc1cc(C(=O)On2ccnc2)ccc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.44
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 4/20 0.44
HSD17B10 Q99714 2/20 0.44
RAB9A P51151 2/20 0.42
KMT2A Q03164 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA13 Q8N1Q1 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
NPC1 O15118 1/20 0.39
CASP3 P42574 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28387353 0.81 HTT (0.50) KMT2AMEN1GAATDP1
SCHEMBL29198558 0.78 TBXAS1 (0.41) ALDH1A1KDM4EKMT2AMEN1TDP1
SCHEMBL11298676 0.76 KDM4E (0.44) HPGDALDH1A1KDM4EHSD17B10RAB9A
SCHEMBL28486775 0.75 ADH5 (0.50) KMT2ACA1CA2MEN1TDP1
SCHEMBL28042994 0.74 HTT (0.48) HPGDALDH1A1KMT2AGAATDP1
SCHEMBL27352183 0.73 CYP19A1 (0.44) RAB9AKMT2ANPC1MEN1TDP1
SCHEMBL28168115 0.73 HTT (0.47) HPGDALDH1A1KMT2AGAATDP1
SCHEMBL27694020 0.72 KDM4E (0.50) HPGDALDH1A1KDM4EHSD17B10RAB9A
SCHEMBL27831008 0.72 ALDH1A1 (0.47) HPGDALDH1A1KDM4ERAB9AKMT2A
SCHEMBL12373225 0.71 KDM4E (0.52) HPGDALDH1A1KDM4EHSD17B10RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104031401-B A kind of preparation method of C.I. pigment Yellow 12 8 山东宇虹新颜料股份有限公司 2016-08-24 CN disclosed