Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL7921892 | 0.86 | NPC1 (0.41) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL6433465 | 0.84 | NPC1 (0.37) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL16239749 | 0.84 | NPC1 (0.37) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL4469957 | 0.83 | NPC1 (0.45) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL6302943 | 0.82 | NPC1 (0.44) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL7634665 | 0.82 | NPC1 (0.44) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL1081333 | 0.80 | NPC1 (0.39) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL8065202 | 0.79 | NPC1 (0.41) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL6908139 | 0.79 | NPC1 (0.39) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL7040232 | 0.78 | RAB9A (0.39) | NPC1RAB9APNMTHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2218725-B1 | BRIDGED METALLOCENE OLEFIN POLYMERIZATION CATALYST AND ETHYLENE POLYMER OBTAINED BY USING THE CATALYST | MITSUI CHEMICALS INC (JP) | 2013-10-23 | — | — | EP | disclosed |
| EP-2218725-A1 | BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST USING THE COMPOUND AND ETHYLENE POLYMER OBTAINED BY USING THE CATALYST | Mitsui Chemicals, Inc. (JP) | 2010-08-18 | — | — | EP | disclosed |