Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | MARK3 | P27448 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.35 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28079449 | 0.88 | RXRA (0.44) | RXRARXRBRXRGCTSSCTSK | |
| SCHEMBL7587408 | 0.83 | AR (0.41) | S1PR1 | |
| SCHEMBL27821346 | 0.81 | RXRA (0.48) | RXRARXRBRXRGCTSSCTSK | |
| SCHEMBL31622482 | 0.79 | RXRA (0.48) | RXRARXRBRXRGCTSSCTSK | |
| SCHEMBL29955074 | 0.78 | RXRA (0.49) | RXRARXRBRXRGCTSSCTSK | |
| SCHEMBL15194036 | 0.78 | RXRA (0.49) | RXRARXRBRXRGCTSSCTSK | |
| SCHEMBL19491488 | 0.77 | CTSS (0.46) | RXRARXRBRXRGCTSSCTSK | |
| SCHEMBL26245660 | 0.76 | RXRA (0.47) | RXRARXRBRXRGCTSSCTSK | |
| SCHEMBL30597890 | 0.76 | RXRA (0.49) | RXRARXRBRXRGCTSSCTSK | |
| SCHEMBL1293281 | 0.76 | RXRA (0.49) | RXRARXRBRXRGCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104144927-B | S1p receptor modulators | 明治制果药业株式会社 | 2016-08-24 | — | — | CN | disclosed |