Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 9/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.34 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15194036 | 1.00 | RXRA (0.49) | RXRARXRBRXRGCTSSCTSK | |
| SCHEMBL29952370 | 0.85 | MGLL (0.40) | RXRARXRBRXRGMGLLTRPA1 | |
| SCHEMBL13554241 | 0.82 | MGLL (0.35) | RXRARXRBRXRGMGLL | |
| SCHEMBL22828 | 0.81 | ENPP2 (0.42) | CTSSCTSKMGLLS1PR1 | |
| SCHEMBL29830169 | 0.81 | ENPP2 (0.42) | CTSSCTSKMGLLS1PR1 | |
| SCHEMBL2997367 | 0.79 | KCNK3 (0.41) | RXRARXRBRXRGMGLL | |
| SCHEMBL28079310 | 0.78 | RXRA (0.47) | RXRARXRBRXRGCTSSCTSK | |
| SCHEMBL9258 | 0.78 | KCNQ3 (0.39) | P2RX3 | |
| SCHEMBL29955864 | 0.77 | RXRA (0.50) | RXRARXRBRXRGCTSSCTSK | |
| SCHEMBL3113375 | 0.77 | RXRA (0.50) | RXRARXRBRXRGCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |