Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28079605 | 0.81 | RORC (0.48) | LMNATP53L3MBTL1 | |
| SCHEMBL22570215 | 0.81 | RORC (0.48) | LMNATP53L3MBTL1 | |
| SCHEMBL28079474 | 0.81 | MEN1 (0.46) | LMNATP53 | |
| SCHEMBL28079472 | 0.80 | POLB (0.44) | LMNATP53 | |
| SCHEMBL28079511 | 0.78 | RORC (0.56) | LMNATP53 | |
| SCHEMBL28079361 | 0.77 | L3MBTL1 (0.44) | L3MBTL1 | |
| SCHEMBL28079359 | 0.77 | RORC (0.52) | SIGMAR1TP53 | |
| SCHEMBL28079360 | 0.76 | RORC (0.53) | SIGMAR1LMNATP53L3MBTL1 | |
| SCHEMBL28079479 | 0.75 | RORC (0.54) | SIGMAR1LMNATP53L3MBTL1 | |
| SCHEMBL2231260 | 0.74 | L3MBTL1 (0.42) | SIGMAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693598-A | Method for synthesis of 3-piperidone derivatives through iridium catalytic hydrogenation | 中国科学院大连化学物理研究所 | 2016-06-22 | — | — | CN | disclosed |