Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | GSR | P00390 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599583 | 0.79 | ENPP2 (0.54) | ENPP2MAOBGSRAKR1C3PTGS2 | |
| SCHEMBL20268666 | 0.78 | ENPP2 (0.52) | ENPP2GSRAKR1C3PTGS2 | |
| SCHEMBL8186690 | 0.78 | AKR1C3 (0.58) | ENPP2AKR1C3PTGS2 | |
| SCHEMBL10226596 | 0.76 | PTGS2 (0.65) | AKR1C3PTGS2 | |
| SCHEMBL10916595 | 0.75 | ENPP2 (0.54) | ENPP2GSRAKR1C3PTGS2 | |
| SCHEMBL28228 | 0.75 | ENPP2 (0.54) | ENPP2MAOBGSRAKR1C3PTGS2 | |
| SCHEMBL8954461 | 0.75 | PTGS2 (0.43) | ENPP2GSRAKR1C3PTGS2 | |
| SCHEMBL4321082 | 0.74 | ENPP2 (0.58) | ENPP2GSRAKR1C3PTGS2 | |
| SCHEMBL17981319 | 0.74 | PTGS2 (0.54) | ENPP2MAOBGSRAKR1C3PTGS2 | |
| SCHEMBL6050635 | 0.74 | CES2 (0.64) | AKR1C3PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104193664-B | A kind of synthetic method of imrecoxib | 山东铂源药业有限公司 | 2016-08-24 | — | — | CN | disclosed |