Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469885 | 0.65 | BRD4 (0.37) | BRD4 | |
| SCHEMBL470078 | 0.60 | NPC1 (0.36) | BRD4 | |
| SCHEMBL15086668 | 0.60 | NPC1 (0.37) | BRD4 | |
| SCHEMBL12603786 | 0.59 | ALOX5 (0.41) | RXRA | |
| SCHEMBL15086669 | 0.59 | NPC1 (0.41) | — | |
| SCHEMBL12603775 | 0.58 | AHR (0.50) | — | |
| Acetic Acid SCHEMBL452190 | 0.57 | HSD17B1 (0.40) | — | |
| SCHEMBL469883 | 0.57 | NPC1 (0.35) | — | |
| SCHEMBL468935 | 0.57 | ACACB (0.36) | — | |
| SCHEMBL559918 | 0.57 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104326952-B | Prepare method and its intermediate of pyridazinone compound | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |