SCHEMBL28079855

SCHEMBL28079855

CC(C)(C)OC(=O)C(N=C=O)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CTSS P25774 1/20 0.32
CTSK P43235 1/20 0.32
AAK1 Q2M2I8 1/20 0.31
LMNA P02545 1/20 0.30
KMT2A Q03164 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15411838 1.00 CTSS (0.32) CTSSCTSKAAK1LMNAKMT2A
SCHEMBL1579513 0.82 SMN1; SMN2 (0.35) CA1CA2
SCHEMBL27712487 0.82 SMN1; SMN2 (0.35) CA1CA2
SCHEMBL3400364 0.78 CTSS (0.34) CTSSCTSKAAK1CA1CA2
SCHEMBL3400359 0.78 CTSS (0.34) CTSSCTSKAAK1CA1CA2
SCHEMBL3310723 0.78 CTSS (0.34) CTSSCTSKAAK1CA1CA2
SCHEMBL12484364 0.78 NOS1 (0.33) CTSSCTSKLMNAKMT2ACA1
SCHEMBL14968296 0.78 NOS1 (0.33) CTSSCTSKLMNAKMT2ACA1
SCHEMBL12868609 0.74 ALDH1A1 (0.30)
SCHEMBL2121642 0.73 AAK1 (0.35) CTSSCTSKAAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106117309-A The inhibitor of hepatitis C virus 吉利德科学公司 2016-11-16 CN disclosed
CN-104540832-B Inhibitors of hepatitis C virus 吉利德科学公司 2016-08-24 CN disclosed