Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | LAP3 | P28838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2110683 | 0.91 | TSHR (0.35) | CA1CA2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28276532 | 0.84 | HDAC7 (0.35) | CA1CA2ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL6859082 | 0.80 | ALDH1A1 (0.31) | ALDH1A1TGFBR1TET2EGLN1SLC1A1 | |
| SCHEMBL9480412 | 0.76 | SLC1A2 (0.39) | CA1CA2ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL26525 | 0.76 | TSHR (0.42) | ALDH1A1LAP3 | |
| SCHEMBL7163225 | 0.76 | — | — | |
| SCHEMBL2566927 | 0.75 | ALDH1A1 (0.35) | CA1CA2ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL19821797 | 0.74 | MMP1 (0.34) | CA1CA2ALDH1A1TGFBR1TET2 | |
| SCHEMBL28825811 | 0.74 | TSHR (0.48) | CA1CA2ALDH1A1TGFBR1TET2 | |
| SCHEMBL27769181 | 0.74 | SLC1A1 (0.35) | CA1CA2ALDH1A1TGFBR1TET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777706-B | A kind of 3- [(benzo [d] [1,3] dioxolanes -4- base)-oxygroup] -3- arylprop aminated compounds and its application | 江苏恩华药业股份有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-105777706-A | 3-[(benzo[d][1,3]dioxolane-4-yl)-oxy]-3-arylpropylamine compound and application thereof | 江苏恩华药业股份有限公司 | 2016-07-20 | — | — | CN | disclosed |