SCHEMBL6859082

SCHEMBL6859082

COC(=O)C(=O)OC(N)CC(N)N

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
SLC1A1 P43005 1/20 0.31
TGFBR1 P36897 1/20 0.31
TET2 Q6N021 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28080050 0.80 CA1 (0.32) ALDH1A1SLC1A1TGFBR1TET2EGLN1
SCHEMBL28276532 0.78 HDAC7 (0.35) ALDH1A1SLC1A1
SCHEMBL9480412 0.70 SLC1A2 (0.39) ALDH1A1SLC1A1
SCHEMBL1999156 0.70 LMNA (0.32) SLC1A1
SCHEMBL31538205 0.69 ALDH1A1 (0.47) ALDH1A1TGFBR1TET2EGLN1
SCHEMBL2110683 0.69 TSHR (0.35) SLC1A1
SCHEMBL8295 0.66
SCHEMBL6950834 0.66 ALDH1A1 (0.56) ALDH1A1TGFBR1TET2EGLN1
SCHEMBL12265742 0.66 TSHR (0.48) ALDH1A1TGFBR1TET2EGLN1
SCHEMBL28825811 0.64 TSHR (0.48) ALDH1A1TGFBR1TET2EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1241225-B1 Resins acting as wet strength agents and creping aids and processes for preparing and using the same HERCULES INC (US) 2004-11-17 EP disclosed
US-20030114631-A1 Resins acting as wet strength agents and creping aids and processes for preparing and using the same HERCULES CORPORATION 2003-06-19 US disclosed
EP-1241225-A2 Resins acting as wet strength agents and creping aids and processes for preparing and using the same HERCULES INCORPORATED (US) 2002-09-18 EP disclosed