Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4566258 | 1.00 | FPR2 (0.48) | FPR2NFKB1NFKB2RELAACHE | |
| SCHEMBL2228459 | 0.98 | ACHE (0.46) | FPR2NFKB1NFKB2RELAACHE | |
| SCHEMBL1506635 | 0.86 | FPR2 (0.39) | FPR2NFKB1NFKB2RELAACHE | |
| SCHEMBL21552032 | 0.86 | FPR2 (0.39) | FPR2NFKB1NFKB2RELAACHE | |
| SCHEMBL1958483 | 0.86 | FPR2 (0.65) | FPR2NFKB1NFKB2RELAACHE | |
| SCHEMBL1958482 | 0.86 | FPR2 (0.65) | FPR2NFKB1NFKB2RELAACHE | |
| SCHEMBL25332329 | 0.84 | FPR2 (0.62) | FPR2NFKB1NFKB2RELAACHE | |
| SCHEMBL6129416 | 0.83 | ACHE (0.65) | FPR2NFKB1NFKB2RELAACHE | |
| SCHEMBL667165 | 0.83 | ACHE (0.65) | FPR2NFKB1NFKB2RELAACHE | |
| SCHEMBL30072208 | 0.83 | ACHE (0.65) | FPR2NFKB1NFKB2RELAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103533833-B | Blood fat reducing antidiabetic | 西蒂斯制药有限责任公司 | 2016-08-31 | — | — | CN | disclosed |