SCHEMBL1958482

SCHEMBL1958482

CCCCCCCCCCCC(O)C(O)/C=C/C=C/C=C/C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 2/20 0.65
NFKB1 P19838 1/20 0.65
NFKB2 Q00653 1/20 0.65
RELA Q04206 1/20 0.65
ACHE P22303 1/20 0.59
BACE1 P56817 1/20 0.59
PPARG P37231 2/20 0.43
GPR132 Q9UNW8 1/20 0.43
GPR84 Q9NQS5 5/20 0.43
FFAR1 O14842 1/20 0.43
OXER1 Q8TDS5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1958483 1.00 FPR2 (0.65) FPR2NFKB1NFKB2RELAACHE
SCHEMBL25332329 0.98 FPR2 (0.62) FPR2NFKB1NFKB2RELAACHE
SCHEMBL18398852 0.92 FPR2 (0.56) FPR2NFKB1NFKB2RELAACHE
SCHEMBL18398851 0.92 FPR2 (0.56) FPR2NFKB1NFKB2RELAACHE
SCHEMBL4566258 0.86 FPR2 (0.48) FPR2NFKB1NFKB2RELAACHE
SCHEMBL28080055 0.86 FPR2 (0.48) FPR2NFKB1NFKB2RELAACHE
SCHEMBL1015737 0.85 FPR2 (0.56) FPR2NFKB1NFKB2RELAACHE
SCHEMBL1015738 0.85 FPR2 (0.56) FPR2NFKB1NFKB2RELAACHE
SCHEMBL9478232 0.85 ACHE (0.69) FPR2NFKB1NFKB2RELAACHE
SCHEMBL31323256 0.85 ACHE (0.69) FPR2NFKB1NFKB2RELAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240173285-A1 COMPOSITIONS COMPRISING EPA AND METHODS OF USING THE SAME FOR TREATING AND/OR PREVENTING ENDOTHELIAL DYSFUNCTION IN A SUBJECT AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) 2024-05-30 US claimed
EP-4329742-A1 COMPOSITIONS COMPRISING EPA AND METHODS OF USING THE SAME FOR TREATING AND/OR PREVENTING ENDOTHELIAL DYSFUNCTION IN A SUBJECT Amarin Pharmaceuticals Ireland Limited (IE) 2024-03-06 EP claimed
CN-115698252-A Dairy product composition 生物乳业公司 2023-02-03 CN claimed
EP-3502703-A1 METHOD FOR THE ASSESSMENT OF NAFLD Metanomics Health GmbH (DE) 2019-06-26 EP claimed
US-20260041696-A1 IN-SITU PRODUCTION OF ANTI-INFLAMMATORY LIPIDS USING MILK FAT GLOBULES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-02-12 US disclosed
US-12479816-B2 20-HETE formation inhibitors University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2025-11-25 US disclosed
US-20250281926-A1 SAMPLE MANIPULATION AND ASSAY WITH RAPID TEMPERATURE CHANGE ESSENLIX CORPORATION (US) 2025-09-11 US disclosed
US-20250262276-A1 METHODS OF INHIBITING BOVINE MASTITIS DURING THE DRY PERIOD ELANCO US INC (US) 2025-08-21 US disclosed
US-20250099965-A1 RAPID SAMPLE TEMPERATURE CHANGING FOR ASSAYING ESSENLIX CORPORATION (US) 2025-03-27 US disclosed
US-12226769-B2 Sample manipulation and assay with rapid temperature change ESSENLIX CORPORATION (US) 2025-02-18 US disclosed
US-12064771-B2 Rapid sample temperature changing for assaying ESSENLIX CORPORATION (US) 2024-08-20 US disclosed
US-20240173285-A1 COMPOSITIONS COMPRISING EPA AND METHODS OF USING THE SAME FOR TREATING AND/OR PREVENTING ENDOTHELIAL DYSFUNCTION IN A SUBJECT AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) 2024-05-30 US disclosed
EP-2607902-A1 Markers of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) and methods of use thereof Lipomics Technologies, Inc. (US) 2013-06-26 EP disclosed
EP-2507633-A1 MEANS AND METHODS FOR DIAGNOSING MULTIPLE SCLEROSIS Metanomics Health GmbH (DE) 2012-10-10 EP disclosed
US-20120238028-A1 Means and Methods for Diagnosing Multiple Sclerosis METANOMICS HEALTH GMBH (DE) 2012-09-20 US disclosed
WO-2011067243-A1 MEANS AND METHODS FOR DIAGNOSING MULTIPLE SCLEROSIS METANOMICS HEALTH GMBH (DE) 2011-06-09 WO disclosed
US-20100233724-A1 MARKERS OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) AND NON-ALCOHOLIC STEATOHEPATITIS (NASH) AND METHODS OF USE THEREOF METABOLON, INC. 2010-09-16 US disclosed
US-6534282-B2 Measurement concentration of hydroxyeicostrienoic acid DETROIT R&D, INC. 2003-03-18 US disclosed
US-6440682-B1 ASSESSING HYPERTENSION BY MEASURING THE AMOUNT OF FREE AND CONJUGATED HYDROXYEICOSATRIENOIC ACIDS (DHETS) AND METABOLITES OF DHETS, WHICH ARE METABOLITES OF ARACHIDONIC ACID EPOXYGENASES AND EPOXIDE HYDROLASES DETROIT R&D INC. 2002-08-27 US disclosed
US-20020025544-A1 Detection of hypertension using immunoreactive metabolic products DETROIT R&D, INC. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041696-A1 IN-SITU PRODUCTION OF ANTI-INFLAMMATORY LIPIDS USING MILK FAT GLOBULES ALOX5, ALOX15, ALOX15B FPR2 285/4885NFKB1 702/4885NFKB2 1407/4885
US-12479816-B2 20-HETE formation inhibitors CYP4A22, ALOX5, ALOX15 FPR2 869/4885NFKB1 1522/4885NFKB2 1141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.