Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20558230 | 0.91 | CHRM2 (0.40) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1416753 | 0.89 | ALOX15 (0.46) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1416487 | 0.89 | ALOX15 (0.46) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL16244348 | 0.89 | ALOX15 (0.46) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1416484 | 0.89 | ALOX15 (0.46) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1416924 | 0.85 | FAAH (0.50) | CYP2C19ALOX15CYP1A2MEN1FAAH | |
| SCHEMBL1416926 | 0.85 | FAAH (0.50) | CYP2C19ALOX15CYP1A2MEN1FAAH | |
| SCHEMBL28427579 | 0.84 | ALOX15 (0.41) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1416787 | 0.83 | FAAH (0.58) | LMNACHRM1CYP2C19ALOX15CYP1A2 | |
| SCHEMBL28536040 | 0.83 | LMNA (0.40) | LMNACHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105712998-A | Azaindole derivatives, preparation method and applications thereof in medicine | 上海润诺生物科技有限公司 | 2016-06-29 | — | — | CN | disclosed |