SCHEMBL16244348

SCHEMBL16244348

CCC/C=C\CCOC(N)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.46
CHRM2 P08172 2/20 0.43
CHRM4 P08173 2/20 0.43
CHRM5 P08912 2/20 0.43
CHRM1 P11229 2/20 0.43
CHRM3 P20309 2/20 0.43
LMNA P02545 2/20 0.43
CYP2C19 P33261 2/20 0.43
CHRNB2 P17787 2/20 0.43
CHRNA4 P43681 2/20 0.43
HTR1A P08908 1/20 0.43
TSHR P16473 1/20 0.43
CHRNA7 P36544 1/20 0.43
FAAH O00519 3/20 0.39
SOAT1 P35610 2/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28080557 0.89 LMNA (0.46) ALOX15CHRM2CHRM4CHRM5CHRM1
SCHEMBL1416924 0.88 FAAH (0.50) ALOX15CYP2C19FAAHSOAT1MEN1
SCHEMBL1416926 0.88 FAAH (0.50) ALOX15CYP2C19FAAHSOAT1MEN1
SCHEMBL1416484 0.87 ALOX15 (0.46) ALOX15CHRM2CHRM4CHRM5CHRM1
SCHEMBL1416753 0.87 ALOX15 (0.46) ALOX15CHRM2CHRM4CHRM5CHRM1
SCHEMBL1416487 0.87 ALOX15 (0.46) ALOX15CHRM2CHRM4CHRM5CHRM1
SCHEMBL1416585 0.83 ALOX15 (0.46) ALOX15CHRM2CHRM4CHRM5CHRM1
SCHEMBL1416727 0.83 ALOX15 (0.46) ALOX15CHRM2CHRM4CHRM5CHRM1
SCHEMBL1416586 0.83 ALOX15 (0.46) ALOX15CHRM2CHRM4CHRM5CHRM1
SCHEMBL20558230 0.80 CHRM2 (0.40) ALOX15CHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2755949-B1 FUNGICIDAL 4-SUBSTITUTED-3-{PHENYL[(HETEROCYCLYLMETHOXY)IMINO]METHYL}-1,2,4-OXADIZOL-5(4H)-ONE DERIVATIVES BAYER IP GMBH (DE) 2015-10-21 EP disclosed
US-9090600-B2 Fungicidal 4-substituted-3-{phenyl[(heterocyclylmethoxy)imino]methyl}-1,2,4-oxadizol-5(4H)-one derivatives BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-07-28 US disclosed
US-20140349848-A1 FUNGICIDAL 4-SUBSTITUTED-3--1,2,4-OXADIZOL-5(4H)-ONE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140349848-A1 FUNGICIDAL 4-SUBSTITUTED-3--1,2,4-OXADIZOL-5(4H)-ONE DERIVATIVES CYP4X1, CYP4B1, CYP4Z1 ALOX15 2823/4885CHRM2 605/4885CHRM4 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.