Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28203632 | 0.79 | KEAP1 (0.53) | PKMHPGDALDH1A1KDM4EKEAP1 | |
| SCHEMBL12054668 | 0.78 | KEAP1 (0.75) | HPGDALDH1A1MAPTKDM4EKEAP1 | |
| SCHEMBL26043484 | 0.75 | HPGD (0.61) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9502908 | 0.75 | HPGD (0.52) | PKMHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL31041151 | 0.72 | KIF11 (0.79) | HPGDALDH1A1MAPTKDM4EKEAP1 | |
| SCHEMBL56693 | 0.72 | KEAP1 (1.00) | PKMHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL28824858 | 0.72 | MAPT (0.60) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16261606 | 0.70 | MAPT (0.63) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11512295 | 0.70 | KEAP1 (0.95) | HPGDALDH1A1KDM4EKEAP1LMNA | |
| Hydrogen Sulfide SCHEMBL27698561 | 0.70 | KEAP1 (0.95) | HPGDALDH1A1KDM4EKEAP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146407-A | Heteroaryl compound and its purposes | 阿维拉制药公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-102740847-B | Heteroaryl compounds and uses thereof | 阿维拉制药公司 | 2016-06-29 | — | — | CN | disclosed |