Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MET | P08581 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28049121 | 0.86 | MET (0.65) | METPIK3C3 | |
| SCHEMBL28074661 | 0.84 | MET (0.46) | MAPTMETKDM4ESMN1; SMN2NTRK1 | |
| SCHEMBL28094884 | 0.79 | MET (0.76) | MAPTMETKMT2AMEN1COMT | |
| SCHEMBL1093217 | 0.77 | RPS6KA5 (0.40) | METPOLBNTRK1 | |
| SCHEMBL28246139 | 0.69 | MEN1 (0.62) | MAPTMETKMT2AMEN1POLB | |
| SCHEMBL27969602 | 0.69 | IKBKB (0.49) | MAPTKMT2AMEN1KDM4EGAA | |
| SCHEMBL28111978 | 0.69 | IKBKB (0.48) | METKMT2AMEN1GAAPIK3C3 | |
| SCHEMBL25269193 | 0.69 | HSP90AA1 (0.46) | MAPTKMT2AMEN1POLBDUSP3 | |
| SCHEMBL5531006 | 0.69 | AXL (0.54) | MAPTKMT2AMEN1POLBDUSP3 | |
| SCHEMBL29598321 | 0.68 | RPS6KA5 (0.45) | METNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641868-A | Inhibitors of influenza viruses replication and its application method and purposes | 广东东阳光药业有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-105906631-A | Compounds and methods for kinase modulation, and indications therefor | 普莱希科公司 | 2016-08-31 | — | — | CN | disclosed |