Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28082101 | 1.00 | L3MBTL1 (0.46) | L3MBTL1RAB9AALDH1A1HPGDCES2 | |
| SCHEMBL28082102 | 1.00 | L3MBTL1 (0.46) | L3MBTL1RAB9AALDH1A1HPGDCES2 | |
| SCHEMBL28082086 | 0.84 | MAPT (0.48) | L3MBTL1RAB9AALDH1A1HPGDGAA | |
| SCHEMBL28082082 | 0.84 | L3MBTL1 (0.41) | L3MBTL1RAB9AALDH1A1HPGDCES2 | |
| SCHEMBL28082084 | 0.84 | L3MBTL1 (0.41) | L3MBTL1RAB9AALDH1A1HPGDCES2 | |
| SCHEMBL28082085 | 0.84 | MAPT (0.48) | L3MBTL1RAB9AALDH1A1HPGDGAA | |
| SCHEMBL18128263 | 0.83 | HSPB1 (0.43) | L3MBTL1RAB9AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL18128155 | 0.83 | HSPB1 (0.43) | L3MBTL1RAB9AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28082062 | 0.83 | MAPT (0.42) | L3MBTL1ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL28082061 | 0.83 | MAPT (0.42) | L3MBTL1ALDH1A1HPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814054-A | Fused imidazole and pyrazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |