Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28082084 | 1.00 | L3MBTL1 (0.41) | L3MBTL1MAPTSMN1; SMN2MAPK1TDP1 | |
| SCHEMBL28082102 | 0.84 | L3MBTL1 (0.46) | L3MBTL1MAPTSMN1; SMN2MAPK1TDP1 | |
| SCHEMBL28082101 | 0.84 | L3MBTL1 (0.46) | L3MBTL1MAPTSMN1; SMN2MAPK1TDP1 | |
| SCHEMBL28082113 | 0.84 | L3MBTL1 (0.46) | L3MBTL1MAPTSMN1; SMN2MAPK1TDP1 | |
| SCHEMBL18128242 | 0.83 | SMN1; SMN2 (0.38) | MAPTSMN1; SMN2TDP1ALDH1A1LMNA | |
| SCHEMBL18342757 | 0.82 | LMNA (0.46) | L3MBTL1MAPTSMN1; SMN2MAPK1TDP1 | |
| SCHEMBL28082062 | 0.81 | MAPT (0.42) | L3MBTL1MAPTSMN1; SMN2MAPK1TDP1 | |
| SCHEMBL28082061 | 0.81 | MAPT (0.42) | L3MBTL1MAPTSMN1; SMN2MAPK1TDP1 | |
| SCHEMBL7029965 | 0.80 | TDP1 (0.41) | L3MBTL1MAPTSMN1; SMN2MAPK1TDP1 | |
| SCHEMBL7022634 | 0.80 | MMP2 (0.36) | MAPTSMN1; SMN2MAPK1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814054-A | Fused imidazole and pyrazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |