Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 9/20 | 0.65 |
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | NPC1 | O15118 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | HTT | P42858 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | STAT1 | P42224 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | RAF1 | P04049 | 1/20 | 0.61 |
| ▸ | IDH1 | O75874 | 1/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28082142 | 0.85 | RAB9A (0.73) | TSHRTP53RAB9AMAPTNPC1 | |
| SCHEMBL4893387 | 0.85 | TP53 (0.87) | TSHRTP53RAB9AMAPTNPC1 | |
| SCHEMBL31040569 | 0.85 | TP53 (0.87) | TSHRTP53RAB9AMAPTNPC1 | |
| SCHEMBL14442613 | 0.84 | TP53 (0.84) | TSHRTP53RAB9AMAPTNPC1 | |
| SCHEMBL17084260 | 0.83 | TP53 (0.84) | TSHRTP53RAB9AMAPTNPC1 | |
| SCHEMBL309673 | 0.83 | LMNA (0.60) | TSHRSMN1; SMN2KMT2AHTTLMNA | |
| SCHEMBL5852120 | 0.82 | TP53 (0.82) | TSHRTP53RAB9AMAPTNPC1 | |
| SCHEMBL21750961 | 0.82 | TSHR (0.82) | TSHRTP53RAB9AMAPTNPC1 | |
| SCHEMBL22103791 | 0.82 | TSHR (0.82) | TSHRTP53RAB9AMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL20502482 | 0.82 | LMNA (0.59) | TSHRTP53SMN1; SMN2KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570723-B | Pyrazolopyrimidine derivative and preparation method thereof and the purposes in prepared by medicine | 广西梧州制药（集团）股份有限公司 | 2016-07-13 | — | — | CN | disclosed |