Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.73 |
| ▸ | NPC1 | O15118 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.61 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171658 | 0.88 | LMNA (0.79) | RAB9ANPC1SMN1; SMN2CA1CA2 | |
| SCHEMBL11092496 | 0.86 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2CA1CA2 | |
| SCHEMBL28082173 | 0.85 | TSHR (0.74) | RAB9ANPC1SMN1; SMN2LMNAGAA | |
| SCHEMBL3468171 | 0.83 | LMNA (0.64) | RAB9ANPC1SMN1; SMN2CA1CA2 | |
| SCHEMBL18500598 | 0.83 | MAPT (0.61) | RAB9ANPC1SMN1; SMN2CA1CA2 | |
| SCHEMBL3116450 | 0.82 | PGR (0.73) | RAB9ANPC1SMN1; SMN2CA1CA2 | |
| SCHEMBL4668688 | 0.82 | LMNA (0.72) | RAB9ANPC1SMN1; SMN2CA1CA2 | |
| SCHEMBL17628550 | 0.80 | RAB9A (0.88) | RAB9ANPC1SMN1; SMN2CA1CA2 | |
| SCHEMBL12010894 | 0.80 | PGR (0.68) | RAB9ANPC1SMN1; SMN2LMNAGAA | |
| SCHEMBL12010877 | 0.79 | PGR (0.70) | RAB9ANPC1SMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570723-B | Pyrazolopyrimidine derivative and preparation method thereof and the purposes in prepared by medicine | 广西梧州制药（集团）股份有限公司 | 2016-07-13 | — | — | CN | disclosed |