Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | GMNN | O75496 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2808152 | 0.87 | DGKA (0.39) | LMNAALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL8562712 | 0.81 | ALDH1A1 (0.46) | LMNAALDH1A1TP53TSHR | |
| SCHEMBL2569827 | 0.81 | DGKA (0.47) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL5108551 | 0.78 | DGKA (0.53) | LMNAMAPTMAPK1ALDH1A1MEN1 | |
| SCHEMBL394258 | 0.78 | DGKA (0.53) | LMNAMAPTMAPK1ALDH1A1MEN1 | |
| SCHEMBL8401967 | 0.78 | DGKA (0.53) | LMNAMAPTMAPK1ALDH1A1MEN1 | |
| SCHEMBL127507 | 0.77 | LMNA (0.83) | LMNAMAPTMAPK1ALDH1A1CYP1A2 | |
| Butane SCHEMBL20558824 | 0.77 | LMNA (0.68) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL10558076 | 0.77 | DGKA (0.52) | LMNAMAPTMAPK1ALDH1A1MEN1 | |
| SCHEMBL6560632 | 0.77 | LMNA (0.36) | LMNAMAPTALDH1A1CYP1A2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034547-B1 | A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-10-09 | — | — | EP | claimed |
| EP-3034545-A1 | A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom | SABIC Global Technologies B.V. (NL) | 2016-06-22 | — | — | EP | claimed |
| EP-3034547-A1 | A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block and the products obtained therefrom | SABIC Global Technologies B.V. (NL) | 2016-06-22 | — | — | EP | claimed |
| EP-3577171-B1 | AQUEOUS SYSTEM FOR FORMING A COATING ON A SUBSTRATE | BASF SE (DE) | 2020-11-18 | — | — | EP | disclosed |
| EP-3034545-B1 | A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2020-11-04 | — | — | EP | disclosed |
| US-10815383-B2 | Pigmented primer composition for forming an n-acyl urea coating | BASF SE (DE) | 2020-10-27 | — | — | US | disclosed |
| EP-3233974-B1 | A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2020-02-19 | — | — | EP | disclosed |
| EP-3328945-B1 | PIGMENTED PRIMER COMPOSITION FOR FORMING AN N-ACYL UREA COATING | BASF SE (DE) | 2019-10-30 | — | — | EP | disclosed |
| US-10457767-B2 | Method of preparing a polycarbodiimide polymer and polycarbodiimide polymer prepared thereby | BASF SE (DE) | 2019-10-29 | — | — | US | disclosed |
| EP-3034546-B1 | A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-10-16 | — | — | EP | disclosed |
| EP-3034544-B1 | A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-10-16 | — | — | EP | disclosed |
| WO-2009045941-A1 | ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM | WORLD MINERALS, INC. (US) | 2009-04-09 | — | — | WO | disclosed |
| US-20060276339-A1 | Methods and compositions for increasing the efficacy of biologically-active ingredients | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2006-12-07 | — | — | US | disclosed |
| US-6489503-B1 | COMPOSITION COMPRISING METHYLENE BIS(PHENYLISOCYANATE) COMPONENT AND POSITIVE AMOUNT OF URETONIMINE, WHICH IS STORAGE STABLE AS LIQUID AT TEMPERATURE OF AT LEAST 30 DEGREES C. | BASF CORPORATION | 2002-12-03 | — | — | US | disclosed |
| US-6120699-A | CONVERTING A PORTION OF THE 4,4'-MDI INTO A POSITIVE AMOUNT OF A CARBODIIMIDE, THE CARBODIIMIDE SUBSEQUENTLY BEING CONVERTED INTO A POSITIVE AMOUNT OF A URETONIMINE IN THE PRESENCE OF EXCESS 4,4'-MDI | BASF CORPORATION (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0989116-A1 | Storage stable methylene bis(phenylisocyanate) compositions | Basf Corporation (US) | 2000-03-29 | — | — | EP | disclosed |
| US-4424288-A | Carbodiimide-modified polymethylene polyphenylene polyisocyanates for use in the preparation of polyisocyanurate-polyurethane foams | BASF WYANDOTTE CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |
| US-4284730-A | Liquid carbodiimide- and uretonimine-isocyanurate-containing polyisocyanate compositions and microcellular foams made therefrom | BASF WYANDOTTE CORPORATION (US) | 1981-08-18 | — | — | US | disclosed |
| US-4228095-A | Process for the preparation of liquid carbodiimide-modified organic polyisocyanates employing organotin catalysts | BASF WYANDOTTE CORPORATION (US) | 1980-10-14 | — | — | US | disclosed |
| US-4018708-A | TRANSESTERIFICATION CATALYSTS | BASF WYANDOTTE CORPORATION (US) | 1977-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276339-A1 | Methods and compositions for increasing the efficacy of biologically-active ingredients | ENPP1, ENPP3, SMPD1 | LMNA 3199/4885MAPT 4463/4885MAPK1 3407/4885 |
| US-10457767-B2 | Method of preparing a polycarbodiimide polymer and polycarbodiimide polymer prepared thereby | PAICS, PBRM1, PARG | LMNA 2029/4885MAPT 695/4885MAPK1 2502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.