Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3656023 | 0.80 | ALDH1A1 (0.48) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL14909620 | 0.80 | ALDH1A1 (0.43) | POLBKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL31439998 | 0.79 | HDAC8 (0.44) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL4718492 | 0.76 | ALDH1A1 (0.39) | POLBKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL28083442 | 0.75 | ALDH1A1 (0.41) | POLBKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL5861345 | 0.74 | ALDH1A1 (0.49) | POLBKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL25295627 | 0.74 | KMT2A (0.46) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31169362 | 0.74 | KMT2A (0.46) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11540231 | 0.74 | ALDH1A1 (0.44) | POLBKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL4719658 | 0.73 | ALDH1A1 (0.59) | POLBKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103384661-B | Mineralocorticoid receptor antagonists | 默沙东公司 | 2016-08-10 | — | — | CN | disclosed |