Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28083441 | 0.75 | POLB (0.41) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL3656023 | 0.74 | ALDH1A1 (0.48) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL4719658 | 0.73 | ALDH1A1 (0.59) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL27923128 | 0.72 | GAA (0.42) | ALDH1A1MEN1KMT2ATDP1FBP1 | |
| SCHEMBL4197934 | 0.69 | NOS1 (0.58) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL14909620 | 0.69 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL5861345 | 0.69 | ALDH1A1 (0.49) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL4718492 | 0.68 | ALDH1A1 (0.39) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL16975276 | 0.66 | F2 (0.41) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11540231 | 0.66 | ALDH1A1 (0.44) | ALDH1A1POLBMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103384661-B | Mineralocorticoid receptor antagonists | 默沙东公司 | 2016-08-10 | — | — | CN | disclosed |