Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31169320 | 0.86 | ADORA2A (0.44) | ALDH1A1POLBEGFRTDP1ADORA3 | |
| SCHEMBL25298021 | 0.85 | TGM2 (0.47) | ALDH1A1POLBTDP1TGM2MEN1 | |
| SCHEMBL31169362 | 0.83 | KMT2A (0.46) | ALDH1A1ADORA3MEN1KMT2APKM | |
| SCHEMBL25295627 | 0.83 | KMT2A (0.46) | ALDH1A1ADORA3MEN1KMT2APKM | |
| SCHEMBL3656023 | 0.81 | ALDH1A1 (0.48) | ALDH1A1POLBTDP1MEN1KMT2A | |
| SCHEMBL25251690 | 0.78 | NOS1 (0.57) | ALDH1A1CFTRPOLBADORA3TGM2 | |
| SCHEMBL4792680 | 0.76 | MPO (0.46) | ADORA3MPOCYP19A1ADORA2AADORA1 | |
| SCHEMBL1169684 | 0.76 | MPO (0.46) | ADORA3MPOCYP19A1ADORA2AADORA1 | |
| SCHEMBL11155364 | 0.76 | MPO (0.46) | ALDH1A1ADORA3MPOMEN1KMT2A | |
| SCHEMBL14909620 | 0.76 | ALDH1A1 (0.43) | ALDH1A1POLBTDP1MPOMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250059172-A1 | INDAZOLE COMPOUND AND PHARMACEUTICAL | NIPPON SHINYAKU CO., LTD. (JP) | 2025-02-20 | — | — | US | disclosed |
| EP-4458810-A1 | INDAZOLE COMPOUND AND PHARMACEUTICAL | Nippon Shinyaku Co., Ltd. (JP) | 2024-11-06 | — | — | EP | disclosed |
| CN-118748993-A | Indazole compounds and medicaments | 日本新药株式会社 | 2024-10-08 | — | — | CN | disclosed |
| WO-2023127883-A1 | INDAZOLE COMPOUND AND PHARMACEUTICAL | 日本新薬株式会社 | 2023-07-06 | — | — | WO | disclosed |
| US-4146630-A | HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250059172-A1 | INDAZOLE COMPOUND AND PHARMACEUTICAL | MC5R, CYP3A5, PTGIS | ALDH1A1 889/4885CFTR 304/4885POLB 4099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.