Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30404501 | 0.81 | LMNA (0.38) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL29852377 | 0.79 | P4HTM (0.48) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL5044994 | 0.79 | P4HTM (0.54) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| Bupicomide SCHEMBL125601 | 0.79 | NFKB1 (0.73) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL28173335 | 0.78 | KMT2A (0.50) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL28252056 | 0.78 | P4HTM (0.49) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL5755133 | 0.78 | L3MBTL1 (0.49) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL29889518 | 0.77 | CHEK2 (0.48) | KMT2AMAPTP4HTMSIRT6OPRM1 | |
| SCHEMBL6471165 | 0.77 | KMT2A (0.46) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL2357414 | 0.77 | ALDH1A1 (0.67) | KMT2AKDM4EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207508-A | 9H-pyrrolo-bipyridine derivatives | UCB生物制药私人有限公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-103282363-B | Imidazoquinoline derivative and pharmaceutically acceptable salt thereof, preparation method and medical application thereof | 上海恒瑞医药有限公司 | 2016-08-10 | — | — | CN | disclosed |