Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27906164 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL27099727 | 0.78 | RIPK1 (0.33) | ALDH1A1MEN1KMT2AMAOAPTGS1 | |
| SCHEMBL9320965 | 0.76 | MEN1 (0.39) | ALDH1A1TSHRMEN1KMT2AHTT | |
| SCHEMBL21484985 | 0.72 | TSHR (0.46) | ALDH1A1TSHRHPGDHTTLMNA | |
| SCHEMBL5892065 | 0.72 | MEN1 (0.38) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL5892064 | 0.71 | MEN1 (0.39) | ALDH1A1MEN1KMT2ACHRNB2CHRNB4 | |
| SCHEMBL22169092 | 0.70 | TLR8 (0.34) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL2608919 | 0.69 | LMNA (0.38) | ALDH1A1TSHRMEN1KMT2ACHRNB2 | |
| SCHEMBL10444028 | 0.69 | LTA4H (0.46) | ALDH1A1TSHRLMNAMAPTCYP2C19 | |
| SCHEMBL9326850 | 0.69 | MEN1 (0.37) | ALDH1A1TSHRMEN1KMT2ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105906531-A | Preparation method of pimavanserin intermediate | 嘉实（湖南）医药科技有限公司 | 2016-08-31 | — | — | CN | disclosed |