Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439441 | 0.87 | PKM (0.53) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL13872034 | 0.85 | TSHR (0.48) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL1087332 | 0.85 | NPC1 (0.60) | SMN1; SMN2ALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL14085634 | 0.84 | BCHE (0.52) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL23463469 | 0.84 | RAB9A (0.48) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL2030978 | 0.83 | RAB9A (0.64) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL24121107 | 0.83 | PKM (0.44) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL11886544 | 0.82 | LMNA (0.44) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL25993799 | 0.82 | NPC1 (0.49) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL25784599 | 0.82 | LMNA (0.45) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870484-B | Addition-fragmentation oligomers | 3M创新有限公司 | 2016-11-23 | — | — | CN | disclosed |