Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10015772 | 0.94 | PKM (0.51) | PKMSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL13872034 | 0.87 | TSHR (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL28084802 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL1087332 | 0.86 | NPC1 (0.60) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL25784599 | 0.86 | LMNA (0.45) | PKMSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL14085634 | 0.85 | BCHE (0.52) | PKMSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL23463469 | 0.85 | RAB9A (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA | |
| P-Xylene SCHEMBL11360520 | 0.85 | THRB (0.57) | SMN1; SMN2ALDH1A1LMNATDP1POLB | |
| SCHEMBL25993943 | 0.85 | L3MBTL1 (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL24121107 | 0.84 | PKM (0.44) | PKMSMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022104113-A1 | SUBSTITUTED MONO- AND POLY-PHENYL-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS | FACEBOOK TECHNOLOGIES, LLC (US) | 2022-05-19 | — | — | WO | disclosed |
| WO-2022104137-A1 | SUBSTITUTED PROPANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS | FACEBOOK TECHNOLOGIES, LLC (US) | 2022-05-19 | — | — | WO | disclosed |