SCHEMBL28085243

SCHEMBL28085243

C=C[SiH3].CO[Si](C=Cc1ccccc1)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.41
NFE2L2 Q16236 3/20 0.38
GRM4 Q14833 1/20 0.37
TUBB1 Q9H4B7 2/20 0.37
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
TUBA1B P68363 1/20 0.37
TUBA4A P68366 1/20 0.37
TUBB4B P68371 1/20 0.37
TUBB3 Q13509 1/20 0.37
TUBB2A Q13885 1/20 0.37
TUBB8 Q3ZCM7 1/20 0.37
TUBA3E Q6PEY2 1/20 0.37
TUBA1A Q71U36 1/20 0.37
TUBA1C Q9BQE3 1/20 0.37
TUBB6 Q9BUF5 1/20 0.37
TUBB2B Q9BVA1 1/20 0.37
CYP1A1 P04798 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL420281 0.90 TRPA1 (0.48) TRPA1NFE2L2TUBB1TUBB4ATUBB
SCHEMBL420280 0.90 TRPA1 (0.48) TRPA1NFE2L2TUBB1TUBB4ATUBB
SCHEMBL12445254 0.90 TRPA1 (0.48) TRPA1NFE2L2TUBB1TUBB4ATUBB
SCHEMBL28068522 0.89 TRPA1 (0.41) TRPA1NFE2L2TUBB1TUBB4ATUBB
Styrene SCHEMBL27490904 0.89 ALDH1A1 (0.52) TRPA1NFE2L2TUBB1TUBB4ATUBB
SCHEMBL28298756 0.88 NFE2L2 (0.47) TRPA1NFE2L2TUBB1TUBB4ATUBB
SCHEMBL28108034 0.81 TRPA1 (0.41) TRPA1NFE2L2GRM4TUBB1TUBB4A
SCHEMBL20583730 0.80 CYP1A2 (0.40) TRPA1NFE2L2TUBB1TUBB4ATUBB
SCHEMBL3955266 0.80 CYP1A2 (0.40) TRPA1NFE2L2TUBB1TUBB4ATUBB
SCHEMBL5412190 0.78 TRPA1 (0.48) TRPA1NFE2L2TUBB1TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105793305-A Optically clear adhesives for durable plastic bonding 3M创新有限公司 2016-07-20 CN disclosed