SCHEMBL420280

SCHEMBL420280

CO[Si](/C=C/c1ccccc1)(OC)OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.48
MAOB P27338 1/20 0.44
NFE2L2 Q16236 3/20 0.44
TUBB1 Q9H4B7 2/20 0.42
TUBB4A P04350 1/20 0.42
TUBB P07437 1/20 0.42
TUBA3C P0DPH7 1/20 0.42
TUBA1B P68363 1/20 0.42
TUBA4A P68366 1/20 0.42
TUBB4B P68371 1/20 0.42
TUBB3 Q13509 1/20 0.42
TUBB2A Q13885 1/20 0.42
TUBB8 Q3ZCM7 1/20 0.42
TUBA3E Q6PEY2 1/20 0.42
TUBA1A Q71U36 1/20 0.42
TUBA1C Q9BQE3 1/20 0.42
TUBB6 Q9BUF5 1/20 0.42
TUBB2B Q9BVA1 1/20 0.42
CYP1A1 P04798 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12445254 1.00 TRPA1 (0.48) TRPA1MAOBNFE2L2TUBB1TUBB4A
SCHEMBL420281 1.00 TRPA1 (0.48) TRPA1MAOBNFE2L2TUBB1TUBB4A
SCHEMBL28298756 0.98 NFE2L2 (0.47) TRPA1MAOBNFE2L2TUBB1TUBB4A
SCHEMBL28068522 0.90 TRPA1 (0.41) TRPA1MAOBNFE2L2TUBB1TUBB4A
Styrene SCHEMBL27490904 0.90 ALDH1A1 (0.52) TRPA1MAOBNFE2L2TUBB1TUBB4A
SCHEMBL28085243 0.90 TRPA1 (0.41) TRPA1MAOBNFE2L2TUBB1TUBB4A
SCHEMBL28108034 0.90 TRPA1 (0.41) TRPA1MAOBNFE2L2TUBB1TUBB4A
SCHEMBL20583730 0.88 CYP1A2 (0.40) TRPA1NFE2L2TUBB1TUBB4ATUBB
SCHEMBL3955266 0.88 CYP1A2 (0.40) TRPA1NFE2L2TUBB1TUBB4ATUBB
SCHEMBL438310 0.85 MAOB (0.56) TRPA1MAOBNFE2L2TUBB1TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 979 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120041122-A Epoxy resin underfill adhesive and preparation method thereof 深圳先进电子材料国际创新研究院 2025-05-27 CN claimed
CN-118406376-A Single-component heat-conducting gel, and preparation method and application thereof 海南永熙投资合伙企业(有限合伙) 2024-07-30 CN claimed
CN-117209673-B Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2024-04-26 CN claimed
CN-117209673-A Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2023-12-12 CN claimed
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN claimed
US-20200388876-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH SILICON CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-12-10 US claimed
CN-110627974-A High-heat-resistance phosphorus-silicon flame retardant, and preparation method and application thereof 铨盛聚碳科技股份有限公司 2019-12-31 CN claimed
CN-110312766-A coating composition, coating film and electromagnetic interference shielding composite material 株式会社LG化学 2019-10-08 CN claimed
CN-110305617-A A kind of dual-component polyurethane car light sealant, preparation method and the application in car light sealing 杭州之江新材料有限公司 2019-10-08 CN claimed
CN-107001067-B Method for producing inorganic fine particle dispersion, curable composition containing the dispersion, and cured product thereof DIC株式会社 2019-09-20 CN claimed
CN-106867033-B A kind of inorganic matter cladding organic silicon fibre retardant of alternative antimony oxide and the preparation method and application thereof 广东优科艾迪高分子材料有限公司 2019-01-25 CN claimed
US-9822330-B2 Light-degradable material, substrate, and method for patterning the substrate NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-11-21 US claimed
EP-2277938-B1 ORGANOPOLYSILOXANE AND MAKING METHOD SHINETSU CHEMICAL CO (JP) 2017-01-25 EP claimed
EP-1826239-B1 Curable composition and coated article SHINETSU CHEMICAL CO (JP) 2009-08-26 EP claimed
US-20080103276-A1 Method for Controlling Fluidity of Phosphor, Phosphor and Phosphor Paste SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2008-05-01 US claimed
US-6716946-B2 Coating SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-04-06 US claimed
EP-0890580-B1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds BRIDGESTONE CORP (JP) 2003-09-17 EP claimed
US-6228908-B1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds BRIDGESTONE CORPORATION (JP) 2001-05-08 US claimed
US-6008295-A FIRST COUPLING THE LIVING DIENE POLYMER OR COPOLYMER CHAINS OBTAINED BY ANIONIC POLYMERIZATION WITH A TIN HALIDE COUPLING AGENT AND THEN TERMINATING THE REMAINING LIVING POLYMER OR COPOLYMER CHAINS WITH A HYDROCARBOXYSILANE; TIRE TREADS BRIDGESTONE CORPORATION (JP) 1999-12-28 US claimed
EP-0890580-A1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds Bridgestone Corporation (JP) 1999-01-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200388876-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH SILICON CONTAINING ELECTROLYTE ADDITIVES SELENOI, SIK1, SIK2 TRPA1 590/4885MAOB 4042/4885NFE2L2 1172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.