Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19008152 | 0.88 | BACE1 (0.52) | MAP4K4BACE1ALDH1A1CTSD | |
| SCHEMBL19016216 | 0.77 | MAP4K4 (0.44) | MAP4K4BACE1ALDH1A1POLB | |
| SCHEMBL15587412 | 0.77 | ACHE (0.56) | MAP4K4BACE1ALDH1A1 | |
| SCHEMBL19008149 | 0.74 | ALDH1A1 (0.46) | MAP4K4BACE1ALDH1A1POLBCTSD | |
| SCHEMBL23703277 | 0.74 | CARM1 (0.55) | MAP4K4ALDH1A1 | |
| SCHEMBL5022826 | 0.74 | ALDH1A1 (0.51) | BACE1ALDH1A1POLBCTSD | |
| SCHEMBL20528646 | 0.72 | GRIN2B (0.56) | BACE1 | |
| SCHEMBL20803950 | 0.72 | SMN1; SMN2 (0.44) | ALDH1A1POLB | |
| SCHEMBL19008153 | 0.72 | ALDH1A1 (0.56) | BACE1ALDH1A1POLBCTSD | |
| SCHEMBL18626538 | 0.72 | ALDH1A1 (0.60) | BACE1ALDH1A1POLBCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717589-B | For treating or prevent the compound of respiratory syncytial virus disease | 弗·哈夫曼-拉罗切有限公司 | 2016-08-17 | — | — | CN | disclosed |