Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16980401 | 0.84 | RAB9A (0.53) | L3MBTL1POLBRAB9ANPC1HRH3 | |
| SCHEMBL14850003 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL19008152 | 0.81 | BACE1 (0.52) | ALDH1A1 | |
| SCHEMBL16980536 | 0.81 | POLB (0.59) | SMN1; SMN2L3MBTL1ALDH1A1POLBRAB9A | |
| SCHEMBL20804106 | 0.80 | ACHE (0.49) | SMN1; SMN2L3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL17335871 | 0.79 | HRH3 (0.66) | SMN1; SMN2KDM4EALDH1A1POLBRAB9A | |
| SCHEMBL19008146 | 0.78 | MAP4K4 (0.44) | ALDH1A1 | |
| SCHEMBL8338757 | 0.77 | GRIN2B (0.54) | L3MBTL1ALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL14866687 | 0.77 | L3MBTL1 (0.46) | SMN1; SMN2L3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL20528646 | 0.76 | GRIN2B (0.56) | RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633350-B2 | Diphenyl derivatives and uses thereof | NOVARTIS AG (CH) | 2020-04-28 | — | — | US | disclosed |
| US-20190077773-A1 | DIPHENYL DERIVATIVES AND USES THEREOF | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077773-A1 | DIPHENYL DERIVATIVES AND USES THEREOF | MYOF, NGF, MUSK | SMN1; SMN2 7/4885L3MBTL1 1366/4885KDM4E 2168/4885 |
| US-10633350-B2 | Diphenyl derivatives and uses thereof | MYOF, NGF, MUSK | SMN1; SMN2 7/4885L3MBTL1 1366/4885KDM4E 2168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.