Etofamide

Etofamide

SCHEMBL1163863

CCOCCN(Cc1ccc(Oc2ccc([N+](=O)[O-])cc2)cc1)C(=O)C(Cl)Cl

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 6/20 0.46
ALDH1A1 P00352 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
LMNA P02545 2/20 0.45
MC4R P32245 1/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
MAPT P10636 3/20 0.39
CRHBP P24387 2/20 0.39
CRHR2 Q13324 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NPC1 O15118 1/20 0.38
MAPK1 P28482 1/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MYOC Q99972 1/20 0.38
MMP13 P45452 1/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11782643 0.89 LMNA (0.49) KCNH2ALDH1A1SMN1; SMN2LMNAMC4R
SCHEMBL11778961 0.86 LMNA (0.51) KCNH2ALDH1A1SMN1; SMN2LMNAMEN1
SCHEMBL11780000 0.85 MC4R (0.53) KCNH2ALDH1A1SMN1; SMN2LMNAMC4R
Clefamide SCHEMBL672628 0.85 LMNA (0.46) KCNH2ALDH1A1SMN1; SMN2LMNAMC4R
SCHEMBL11780196 0.85 MC4R (0.53) KCNH2ALDH1A1SMN1; SMN2LMNAMC4R
Teclozan SCHEMBL635666 0.84 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL11779835 0.80 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2LMNAMC4RMEN1
SCHEMBL11780202 0.80 ALDH1A1 (0.43) KCNH2ALDH1A1SMN1; SMN2LMNAMEN1
SCHEMBL11780584 0.79 LMNA (0.46) KCNH2ALDH1A1SMN1; SMN2LMNAMC4R
SCHEMBL11780552 0.79 LMNA (0.45) KCNH2ALDH1A1SMN1; SMN2LMNAMC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170291886-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS NEOCULI PTY LTD (AU) 2017-10-12 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20050142069-A1 Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer NOVADEL PHARMA, INC. 2005-06-30 US claimed
EP-1545458-A2 BUCCAL, POLAR OR NON-POLAR SPRAY OR CAPSULE CONTAINING DRUGS FOR TREATING AN INFECTIOUS DISEASE OR CANCER Novadel Pharma Inc. (US) 2005-06-29 EP claimed
WO-2004019912-A2 BUCCAL, POLAR OR NON-POLAR SPRAY OR CAPSULE CONTAINING DRUGS FOR TREATING AN INFECTIOUS DISEASE OR CANCER NOVADEL PHARMA INC. (US) 2004-03-11 WO claimed
US-20030082107-A1 Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer NOVADEL PHARMA INC. 2003-05-01 US claimed
WO-2026090318-A2 ENCAPSULATION COMPOSITIONS AND METHODS FOR ENCAPSULATING ACTIVE AGENTS DEFY-Tech Labs, Inc. (US) 2026-04-30 WO disclosed
US-20260108444-A1 ENCAPSULATION COMPOSITIONS AND METHODS FOR ENCAPSULATING ACTIVE AGENTS DEFY TECH LABS INC (US) 2026-04-23 US disclosed
EP-4092139-B1 METHOD FOR DISCRIMINATING BETWEEN LIVE AND DEAD MICROBES IN A SAMPLE PATHOQUEST (FR) 2026-02-18 EP disclosed
US-20250312349-A1 COMPOSITION AND METHODS OF TREATING INTRACELLULAR PATHOGEN INFECTION UNIV HOSPITALS CLEVELAND MEDICAL CENTER (US) 2025-10-09 US disclosed
US-20020102215-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
WO-2002045693-A1 PHARMACEUTICAL PREPARATION COMPRISING AN ACTIVE DISPERSED ON A MATRIX ALTANA PHARMA AG (DE) 2002-06-13 WO disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108444-A1 ENCAPSULATION COMPOSITIONS AND METHODS FOR ENCAPSULATING ACTIVE AGENTS LIPA, LIPC, ACACA KCNH2 2603/4885ALDH1A1 1598/4885SMN1; SMN2 2432/4885
US-20170291886-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS DPM1, ABCB11, PIGS KCNH2 1884/4885ALDH1A1 840/4885SMN1; SMN2 3002/4885
US-20020102215-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 KCNH2 4230/4885ALDH1A1 4459/4885SMN1; SMN2 1978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.