Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP7 | P55210 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12793853 | 0.86 | GAA (0.63) | CASP7CASP3TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL5605322 | 0.77 | POLB (0.61) | CASP7ATMTSHRCASP1SMN1; SMN2 | |
| SCHEMBL10064237 | 0.76 | PKM (0.63) | CASP7CASP3SMN1; SMN2 | |
| SCHEMBL18954594 | 0.75 | CASP3 (0.57) | CASP7CASP3CASP1 | |
| SCHEMBL27913253 | 0.75 | CASP3 (0.41) | CASP7CASP3CASP1 | |
| SCHEMBL16026507 | 0.74 | ATM (0.58) | ATMTSHRSMN1; SMN2HTTPOLB | |
| SCHEMBL8263983 | 0.74 | CASP3 (0.67) | CASP7CASP3CASP1 | |
| SCHEMBL5988598 | 0.73 | CASP3 (0.79) | CASP7CASP3TSHRCASP1SMN1; SMN2 | |
| SCHEMBL1684564 | 0.73 | TSHR (0.67) | CASP7ATMTSHRCASP1SMN1; SMN2 | |
| SCHEMBL4898697 | 0.73 | CASP3 (0.54) | CASP7CASP3CASP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103183631-B | Isatin-5-sulfonic acid amide derivatives and the application in the medicine of preparation treatment severe acute respiratory syndrome thereof | 天津市国际生物医药联合研究院 | 2016-08-24 | — | — | CN | disclosed |