Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.79 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodixanol SCHEMBL8845042 | 0.91 | LMNA (1.00) | LMNACYP2C19HIF1AEGFRSRC | |
| Iodixanol SCHEMBL37712 | 0.91 | LMNA (1.00) | LMNACYP2C19HIF1AEGFRSRC | |
| Iodixanol SCHEMBL21546 | 0.91 | LMNA (1.00) | LMNACYP2C19HIF1AEGFRSRC | |
| Iodixanol SCHEMBL22645199 | 0.90 | LMNA (0.97) | LMNACYP2C19HIF1AEGFRSRC | |
| Iomeprol SCHEMBL26981 | 0.90 | LMNA (0.63) | LMNACYP2C19HIF1AEGFRSRC | |
| Iohexol SCHEMBL31722694 | 0.89 | CYP2C19 (1.00) | LMNACYP2C19HIF1AEGFRSRC | |
| Iohexol SCHEMBL37920 | 0.89 | CYP2C19 (1.00) | LMNACYP2C19HIF1AEGFRSRC | |
| Iohexol SCHEMBL8844889 | 0.89 | CYP2C19 (1.00) | LMNACYP2C19HIF1AEGFRSRC | |
| Iohexol SCHEMBL26501 | 0.89 | CYP2C19 (1.00) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL12589793 | 0.88 | LMNA (0.93) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |